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High-Protein Spinach Artichoke Chicken Casserole Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 4.7 from 196 reviews
  • Author: Olivia
  • Prep Time: 10 minutes
  • Cook Time: 40 minutes
  • Total Time: 50 minutes
  • Yield: 4 servings 1x
  • Category: Casserole
  • Method: Baking
  • Cuisine: American
  • Diet: Low Fat

Description

This High-Protein Spinach Artichoke Chicken Casserole is a creamy, cheesy, and savory baked dish packed with lean chicken breast, nutritious spinach, and tangy artichoke hearts. The blend of cottage cheese, mozzarella, and parmesan creates a rich, delicious sauce that makes this casserole both comforting and protein-packed, perfect for a wholesome family meal.


Ingredients

Scale

Chicken

  • 1 lb boneless, skinless chicken breast, cut into bite-sized pieces
  • Kosher salt, to taste
  • Black pepper, to taste
  • 1 tsp avocado oil or olive oil

Dairy and Sauce

  • 16 oz cottage cheese (4% fat preferred)
  • 2 garlic cloves, peeled
  • ½ tsp kosher salt
  • ¼ tsp black pepper
  • ¼ tsp onion powder
  • ½ cup low-moisture, part skim, finely shredded mozzarella cheese
  • ⅔ cup finely grated parmesan cheese

Vegetables

  • 1 can artichoke hearts (16 oz), drained and finely chopped
  • 6 oz frozen chopped spinach, thawed

Instructions

  1. Preheat Oven: Preheat your oven to 350°F (175°C) to prepare for baking the casserole.
  2. Dry Brine Chicken (Optional): Season the cubed chicken breast heavily with kosher salt and let it sit at room temperature for 20+ minutes to enhance moisture and flavor.
  3. Prepare Artichokes: Place the drained artichoke hearts into a thin dish towel or paper towel and squeeze out all excess liquid. Finely chop them and set aside.
  4. Prepare Spinach: Using the same towel, squeeze out all excess liquid from the thawed spinach. This step is important to avoid excess moisture in the casserole.
  5. Sear Chicken: Heat a large pan over medium heat and add the oil. Add the cubed chicken in a single layer, season with black pepper, and cook for 2-3 minutes per side until mostly cooked through. Remove and drain any excess grease, then set the chicken aside.
  6. Make Cottage Cheese Sauce: In a small food processor, blend the cottage cheese, garlic, kosher salt, black pepper, and onion powder until smooth and creamy.
  7. Combine Ingredients: In a baking dish, mix the cooked chicken, squeezed spinach, chopped artichokes, blended cottage cheese sauce, and about two-thirds of the mozzarella and parmesan cheeses. Stir until well combined and spread evenly.
  8. Bake Covered: Cover the baking dish with foil and bake in the preheated oven for 20 minutes to allow flavors to meld and the casserole to heat through.
  9. Top and Finish Baking: Remove the foil, sprinkle the remaining mozzarella and parmesan cheese evenly on top, and bake uncovered for another 10 minutes. Optionally, broil for a few minutes at the end to achieve a golden, bubbly crust.
  10. Serve: Remove from oven, let cool slightly, then serve warm. Enjoy your high-protein, flavorful casserole!

Notes

  • Dry brining the chicken enhances flavor and juiciness but is optional if short on time.
  • Be sure to squeeze excess moisture out of spinach and artichokes to prevent a watery casserole.
  • Using part-skim mozzarella keeps the dish lower in fat while still providing good melt and flavor.
  • Switching to broil in the last few minutes gives a nice golden crust but watch carefully to prevent burning.
  • This casserole can be made ahead and refrigerated before baking; add extra bake time if baking cold.