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Chicken and Stuffing Casserole Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 5 from 138 reviews
  • Author: Olivia
  • Prep Time: 20 minutes
  • Cook Time: 40 minutes
  • Total Time: 1 hour
  • Yield: 8 servings 1x
  • Category: Main Dish
  • Method: Baking
  • Cuisine: American

Description

This comforting Chicken and Stuffing Casserole combines savory shredded chicken, mixed vegetables, and sautéed mushrooms and celery with creamy soup and sour cream, all topped with a homemade stuffing mix and melted cheese. Perfect for an easy family dinner, this casserole bakes until bubbly with a crispy golden topping, delivering hearty flavors and satisfying textures in every bite.


Ingredients

Scale

Stuffing

  • 3 cups chicken broth
  • ½ cup salted butter
  • 2 (6-ounce) packages stuffing mix

Filling

  • 2 tablespoons salted butter
  • 1 medium onion, chopped
  • 3 celery stalks, diced
  • 8 ounces mushrooms, chopped
  • ½ teaspoon garlic powder
  • ½ teaspoon black pepper
  • 1 (10.5-ounce) can cream of chicken soup
  • 1 cup sour cream
  • ½ cup chicken broth
  • 1 tablespoon Worcestershire sauce
  • 3 cups shredded, cooked chicken (about 1 whole rotisserie chicken)
  • 1 (12-ounce) bag frozen mixed vegetables, thawed by rinsing under cold water
  • 8 slices shredded cheddar or provolone cheese

Instructions

  1. Prepare the stuffing: Preheat your oven to 375°F. In a medium saucepan, heat 3 cups of chicken broth and ½ cup salted butter until boiling. Remove from heat and stir in the 2 packages of stuffing mix. Toss well to moisten evenly. Cover the pan and let it sit for 5 minutes to absorb the liquid.
  2. Sauté vegetables: In a large skillet, melt 2 tablespoons salted butter over medium heat. Add the chopped onion and diced celery, cooking until they become soft and translucent, about 5 to 7 minutes. Then add the chopped mushrooms, sprinkle with garlic powder and black pepper, and continue cooking until the mushrooms brown, stirring occasionally.
  3. Mix the filling: In a large bowl, whisk together the cream of chicken soup, sour cream, ½ cup chicken broth, and Worcestershire sauce until smooth. Add the shredded cooked chicken, thawed mixed vegetables, and the sautéed vegetables from the skillet. Stir everything well to combine.
  4. Assemble the casserole: Spread the chicken and vegetable mixture evenly into a 9×13-inch casserole or baking dish. Place the 8 cheese slices on top of the mixture, covering it evenly. Then, spread the prepared stuffing mixture over the cheese layer.
  5. Bake the casserole: Place the casserole in the preheated oven and bake uncovered for 40 minutes. Bake until the casserole is heated through and the stuffing topping is lightly browned and crispy.

Notes

  • Make Ahead: You can assemble the casserole, cover it tightly with aluminum foil or plastic wrap, and refrigerate it for up to 3 days before baking. If baking from cold, add 5-10 extra minutes to the cooking time.
  • Storage: Store leftovers in an airtight container in the refrigerator for 3-4 days. To reheat, cover with foil and warm in a 350°F oven for 15-20 minutes until heated through. Alternatively, reheat in the microwave in short intervals to avoid drying out.
  • Freezing: Freeze the casserole in a freezer-safe container or wrap tightly in plastic wrap and foil for up to 3 months. Thaw in the refrigerator before reheating.
  • Homemade Cream of Chicken Soup: For a scratch version, melt 3 tablespoons salted butter in a saucepan. Whisk in ⅓ cup all-purpose flour and cook for 1 minute. Gradually whisk in ⅓ cup chicken broth and ⅓ cup milk until smooth. Season with ¼ teaspoon onion powder, ⅛ teaspoon kosher salt, and ⅛ teaspoon black pepper. Cook until thickened, about 1-2 minutes, then use as a substitute.